Centrioles - critical players in cell division

Centrioles and mitotic spindle in the one-cell C. elegans embryo. Embryo stained for centrioles (SAS-4, red), microtubules and DNA (black).

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists led by Alexander Dammermann at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, now examine how centrioles contribute to this process. The findings, published in “Developmental Cell”, help to elucidate the function of these tiny cellular structures in mitosis.