Recent Research Highlights

A groundbreaking genetic screening tool for human organoids

Researchers from the laboratory of Jürgen Knoblich at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – developed…

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Autophagy: the beginning of the end

Autophagy, from the Greek for ‘self-eating’, is an essential process that isolates and recycles cellular components under conditions of stress or when…

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Detective work in the cell: Scientists uncover a new RNA-modifying enzyme

Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have…

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How the immune system generates a vast antibody repertoire to fight infections

It is long known that the acquired immune system can generate a vast antibody (immunoglobulin) repertoire by gene recombination in developing B-cells.…

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Layered Liquids – reaction chambers for gene regulation

A marvel of complexity, the nucleus is the command center of the cell – harboring information, codes and controlled access. But different from…

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Zebrafish

How decisions unfold in a zebrafish brain

IMP researchers observed the entire brains of zebrafish larvae in unprecedented resolution to reconstruct the neural basis of “left or right” choices…

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Cohesin - a molecular motor that folds our genome

New insights into the process of DNA-looping change our view of how the genome is organised within cells. The discoveries by IMP-researchers elucidate…

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Activation of gene promoters: scientists discover basis of regulatory specificity

IMP scientists from the lab of Alexander Stark show why certain activators - enhancers or cofactor proteins - activate specific promoters. The…

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Deciphering diabetes with game-changing human blood vessels from stem cells

Changes in blood vessels are the major cause of death and morbidity in diabetes. For the first time, scientists managed to grow perfect human blood…

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Building block of "happiness hormones" is key to controlling immunity in cancer and autoimmune diseases

Scientists at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – together with the Boston Children's Hospital at…

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Principles of limb regeneration in salamanders show link to mammals

The Mexican axolotl Ambystoma mexicanum is a popular model organism for studying regeneration. Scientists at the IMP now show the origin of its…

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“Bouncer”, the gate-keeper of the egg, controls sperm entry

Fertilization is fundamental for sexual reproduction, yet its molecular mechanisms are poorly understood. IMP scientists now found a protein that…

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