The Preclinical Imaging Facility (pcIMAG) provides comprehensive multiparametric MR imaging using a state-of-the-art 15.2 Tesla small animal MRI scanner (Bruker, Germany).The facility specializes in in vivo mouse imaging, while we also welcome other smaller model organisms. We also offer comprehensive data processing and visualization tools to help users get the best quality figures.
We offer an extensive list of services with focused applications in neuroscience, cardiac imaging, anatomical characterization of organ systems, and quantitative measurement of perfusion/mean transit time/blood volume. Among the specific applications, we offer cell labeling and tracking, and axonal tract tracing using manganese (Mn2+) MRI.
State-of-the-art spectroscopy data acquisition with the 15.2 Tesla is feasible due to highly optimized shim procedures developed by Bruker Biospin (Ettlingen, Germany). We routinely perform spectroscopy of brain and liver.
Functional magnetic resonance imaging (fMRI) is a technique for measuring brain activity. Regions with higher activation show an increase in blood flow and thus oxygen. fMRI is a tool to measure changes in oxygen concentration and generate an activity map of the brain. This is the best way to study the influence of pharmacological, genetic, or environmental manipulations on brain function.
Quantitative image analysis can be done using information from various parameters such as transverse (T2) and longitudinal (T1) relaxation times, relative perfusion, blood volume, apparent diffusion coefficient, magnetization transfer ratio, and many more.
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We provide access to a state-of-the-art Bruker Biospec 15.2 Tesla MRI scanner equipped with 1 T/m gradient and 11 cm-diameter bore size. The scanner is designed for virtually any small animal MR imaging application in life science, biomedical, and preclinical research.
We are happy to provide MRI scanning and data analysis for you. Currently we do not offer user training, as background knowledge of MRI is required to operate the scanner. If users have previous experience with the Bruker scanner, exceptions can be made. The VBCF General Cooperation Conditions apply.
In case of co-authorship:
The Vienna BioCenter Core Facilities (VBCF) Preclinical Imaging Facility acknowledges funding from the Austrian Federal Ministry of Education, Science and Research and the City of Vienna.
For acknowledging services by the Preclinical Imaging Facility:
The XXXXXX was performed by the Preclinical Imaging Facility at Vienna BioCenter Core Facilities (VBCF), member of the Vienna BioCenter (VBC), Austria.
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