During infection, specialized cells of our innate immune system mount an immediate response to combat invading pathogens. The activation of these immune cells by interferon signaling is key to the resolution of infection. How interferon signaling interacts with other cellular signaling pathways is unclear. The lab of Thomas Decker has now studied the interaction between interferon and stress signaling. Their findings, published in Science Signaling, show that cross-talk between the two pathways modulates immunity in response to infections.
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