Novel Catalase for complete neutralization of H2O2 in agar plates

Eucodis developed and patented a catalase as a novel neutralizer in environmental monitoring media and offers either a collaboration or OEM supply of the enzyme or the technology itself for licensing.

Eucodis’ patented recombinant catalase formulation is unique as it is the only one worldwide that can be applied to agar plates due to its increased stability at high temperatures (stable at 55°C during production and during sterilization by gamma-irradiation).

Hydrogen peroxide vapor is routinely used in disinfection and sterilization of clean rooms and production facilities. It offers many advantages like its universal applicability, simple handling and virtually no residues. However, there are stringent requirements for a safe and effective method to ensure that no traces of H2O2 are present ultimately interfering with the monitoring of the sterilization process.

Currently, agar plates for monitoring the disinfection or sterilization are supplemented with pyruvate, which is however consumed during the neutralization of hydrogen peroxide. Therefore, pyruvate has difficulties in neutralizing higher concentrations and amounts of hydrogen peroxide.

Catalase as a supplement offers a more effective and reliable solution for safe and secure environmental monitoring of sterilization in clean rooms, isolators or production facilities by also removing remaining traces and spots of high concentration of H2O2 when used in agar plates or liquid media.

Eucodis is offering access to the patented technology to interested parties for collaboration in application development. Ready-to-use media plates containing catalase for sterility monitoring and/or OEM supply of the enzyme for your environmental monitoring media or other applications are available.

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