‘Network medicine’ directs disease diagnosis

Rare diseases are usually caused by a single genetic defect. Nevertheless, the search for the cause and the assessment of the effects is highly complex and difficult. Jörg Menche’s Lab has now developed a multiplex network that maps all genes and their interactions on multiple levels of biological organization. Their study, published in Nature Communications, could help scientists better diagnose the causative genetic defects in disease, as well as understand the underlying mechanisms.

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