IMP students characterise a sperm protein essential for zebrafish fertilisation

During fertilisation, egg and sperm rely on a host of membrane proteins to bind and fuse. Two students at the IMP examined the function of Spaca6 – a sperm protein essential for fertilisation in mice – in zebrafish sperm. The scientists found that Spaca6 is also crucial for sperm-egg binding in fish, and that it may act in concert with other sperm proteins. Their findings are now reported in Frontiers in Cell and Developmental Biology.

Zebrafish sperm visualised with Differential Interference Contrast microscopy (magnified 100x). Credit: Karin Panser.

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