IMP Scientists hijack cell machinery to destroy cancer-driving proteins

Every cell carries a built-in cleanup system to remove unwanted proteins, and researchers have learned to harness the enzymes in this system to destroy cancer-driving proteins. Scientists at the IMP and the University of North Carolina at Chapel Hill, have now captured this process in near-atomic 3D resolution, revealing its inner workings in unprecedented detail. Reporting in Nature Communications, they show that hijacked enzymes can destroy cancer-related proteins without compromising their normal function.