An amplified spindle

The Gerlich lab at IMBA - Institute of Molecular Biotechnology shows how molecular self-organization shapes the cell division machinery.

How microtubules form and grow to shape the specific geometry of the spindle is not fully understood. Daniel Gerlich’s group now reports in the Journal of Cell Biology that once a few microtubules have grown out from the two poles of the spindle, most microtubules are generated throughout the spindle body. This results in highly coordinated microtubule growth towards the attachment sites on chromosomes.
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