A refined axolotl genome assembly sheds light on basic cellular processes

After the first assembly of an axolotl genome was published in 2018, the lab of Elly Tanaka teamed up with scientists at the University of Kentucky to take the next step and assembled the genome at the chromosome scale. In a study now published in the journal PNAS, the scientists show that gene regulation in axolotls occurs over very large genomic distances, and that chromosomes are packaged efficiently during mitotic cell divisions.